Until recently, 25-year-old Barry Allen (series star GRANT GUSTIN) lived a normal life as a forensic scientist in the Central City Police department. Barry is deeply in love with his best friend, Iris West (series star CANDICE PATTON), daughter of Barry's surrogate father, Detective Joe West (series star JESSE L. MARTIN), who adopted Barry 14 years ago, after Barry's mother was murdered and his father, Henry Allen (recurring guest star JOHN WESLEY SHIPP), received a life sentence for the crime -- though Barry maintains that a mysterious "Man in Yellow" was responsible.
Nine months ago, the S.T.A.R. Labs Particle Accelerator exploded, creating a dark matter lightning storm that struck Barry - bestowing him with super-speed and making him the fastest man alive. But Barry wasn't the only person who was given extraordinary abilities that night. The dark matter also created meta-humans - many of whom have wreaked havoc on the city. With the help of his new scientist friends at S.T.A.R Labs, Caitlin Snow (series star DANIELE PANABAKER), Cisco Ramon (series star CARLOS VALDES) and Dr. Harrison Wells (series star TOM CAVANAGH), Barry begins a journey as The Flash to protect the people of Central City from these powerful new threats.
However, Barry's mission gets sidetracked when he comes face to face with the Man in Yellow aka The Reverse Flash. In the season one finale, the Reverse Flash is defeated by the noble sacrifice of one of Barry's friends, however a black hole Singularity was opened up over Central City that not only threatened the city, but also might have created a gateway between worlds.
Picking up months after the Singularity attacked Central City, the season two premiere finds Barry still struggling to forgive himself for Eddie's (special guest star RICK COSNETT) death. Concerned about putting his friends in danger, Barry has pushed everyone away and has chosen to protect the city on his own. When a meta-human named Atom Smasher (guest star ADAM COPELAND) attacks the city, however, Iris tells Barry that he needs to let his friends help him protect the citizens of Central City. Meanwhile, Cisco helps Joe with his Meta Task Force.